Supply 313-06-4 good supplierfast delivery Depofemin CAS NO.313-06-4

Estradiol cypionate is the 17 β-cyclopentylpropinate ester of estradiol, which inhibits ET-1 synthesis via estrogen receptor.

Estradiolcypionate is a natural estrogen, a synthetic ester of estradiol. Compared with other commonly used estradiol esters, it was found that estradiol cyclopentapropionate has the longest duration of action of 11 days by intramuscular injection, while estradiol benzoate and estradiol valerate The duration of action is 4-5 days and 7-8 days, respectively. Including the treatment of lack of sexual desire in the absence of follicular cysts, persistent corpus luteum, pyometra, and retained placenta. Possibly, ECP is beneficial to high-risk postpartum diseases by directly or maintaining oxytocin receptor sites in the uterus to stimulate uterine contraction, by increasing uterine blood flow to promote more WBCs to the infected site, enhancing uterine immune function, and by increasing bacterial phagocytosis Function, or the movement of IgA and IgG to the uterine cavity, or promote uterine drainage by delaying the closure of the cervix.

Estradiol is produced especially within the follicles of the female ovaries, but also in other endocrine (i.e., hormone-producing) and non-endocrine tissues (e.g., including fat, liver, adrenal, breast, and neural tissues). Estradiol is biosynthesized from progesterone (arrived at in two steps from cholesterol, via intermediate pregnenolone). One principal pathway then converts progesterone to its 17-hydroxy derivative, 17-Hydroxyprogesterone, and then to 4- androstenedion e via sequential cytochrome P450-catalyzed oxidations.[citation needed] Action of aromatase on 4- androstenedion e generates estrone, and action of a dehydrogenase on this gives the title compound, 17β-estradiol.[citation needed] Alternatively, 4- androstenedion e can be converted into the androgen,  which in turn can be converted directly into 17β-estradiol.