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Home > Products >  High Quality99% On Sale 57-91-0 low price 17α-estradiol

High Quality99% On Sale 57-91-0 low price 17α-estradiol CAS NO.57-91-0

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Quick Details

  • ProName: High Quality99% On Sale 57-91-0 low pr...
  • CasNo: 57-91-0
  • Molecular Formula: C18H24O2
  • Appearance: white powder
  • Application: Estradiol (known as α-Estradiol or 17 ...
  • DeliveryTime: one week
  • PackAge: According to client's requirements
  • Port: shanghai
  • ProductionCapacity: 1-1.5 Metric Ton/Year
  • Purity: 99%
  • Storage: 20kg in stock
  • Transportation: According to client's requirements
  • LimitNum: 0 Metric Ton

Superiority

High Quality99% On Sale 57-91-0 low price 17α-estradiol

Direct production in our own factory with spot stock and quality assurance

DMF (Drug master file) supportable

Competitive manufacturing cost and selling price

 

17α-Estradiol

DMF available

 

Capacity: 1~1.5 MT per Year 

CAS: 57-91-0

Molecule Formula: C18H24O

Molecule Weight: 272.38

Molecule Structure: 

Other Name: Epiestradial,17alpha-Estradiol,Epiestradiol,Epiestrol,3,17-Dihydroxyestratriene

 

Estradiol Usage And Synthesis
Chemical Properties White Solid
Uses Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke.
Definition ChEBI: An estradiol that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17 (the 17alpha stereoisomer).
Biological Activity Endogenous estrogen receptor ligand (K i values are 0.2 and 1.2 nM for ER α and ER β receptors respectively).
Purification Methods 17-Estradiol recrystallises from aqueous EtOH (80%) as the hemihydrate and differs from the -anomer (below) by not precipitating with digitonin in 80% aqueous EtOH. The diacetate [1474-52-8] crystallises from aqueous EtOH in needles with m 139-140o. The 3-benzoate crystallises in three forms m 158o, 153o and 63o.

Details

Function
1. Inadequate estrogen supplementation. Used in the treatment of female gonadal dysfunction, bilateral ovariectomy, atrophic vaginitis, desiccation of the vulva, climacteric syndrome such as hot flashes, sweating and mental and nerve symptoms.

2. Use estrogen to treat metastatic breast cancer, 40 % can achieve relief.

3. To treat advanced prostate cancer, symptoms are markedly improved, pain is reduced, testicular removal is followed by estrogen treatment.

4. Prevent osteoporosis and prevent rapid bone loss due to estrogen deficiency.

Treatment of acne(acne) can be used in heavier cases in men and a combination of estrogen and progesterone in women.

6. Leucopenia, used in malignant tumor caused by chemotherapy or radiotherapy leukopenia, has the effect of obviously raising the white blood cells.

7. Use as an after-pill.

8. Milk withdrawal.
    About us
Janton HealthTech Limited (www.jantonhealth.com) is a developer and manufacturer of health related products, which are currently mainly focused on Chemical Intermediates and APIs for human and animals.
 
Janton HealthTech team has been playing with steroids structures since 2002.
 
Sustainability development is our core philosophy. We keep emphasizing manufacturing efficiency/cost as well as safety/environmental management. What we are doing is offering economical products with good quality and we think highly of our reputation.
 
Besides our own projects, the other half of our businesses is contract R&D and manufacturing for global reputable pharmaceutical customers. We don’t promise that we can make everything well and we sincerely choose projects according to our R&D/Facility strengths. May you have some needs and may you want to try with us, just contact us!

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